Incidence of Trypanosoma cruzi transmission through breastfeeding during acute experimental Chagas disease
Braz. j. infect. dis
;
15(2): 116-118, Mar.-Apr. 2011. ilus
Artigo
em Inglês
| LILACS
| ID: lil-582412
ABSTRACT
OBJECTIVE:
To verify the incidence of T. cruzi transmission through breastfeeding during acute experimental Chagas' disease.METHODS:
Fifteen female Swiss mice were mated and, after pregnancy confirmation, placed in individual cages. A few hours after birth, the females were inoculated with 0.1 mL of blood containing approximately 3 x 10(5) trypomastigote forms of Y strain of T. cruzi and continued breastfeeding for 25 days.RESULTS:
In 142 offspring examined no infection through breast-feeding was observed.CONCLUSIONS:
The low number of trypomastigote forms ingested by the newborn mice combined with biological and biochemical characteristics of blood trypomastigotes may explain the lack of transmission in this experiment.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Aleitamento Materno
/
Doença de Chagas
/
Complicações Parasitárias na Gravidez
Tipo de estudo:
Estudo de incidência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Animais
/
Gravidez
Idioma:
Inglês
Revista:
Braz. j. infect. dis
Assunto da revista:
Doenças Transmissíveis
Ano de publicação:
2011
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Faculdade de Medicina de Marília/BR
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