Infection of the lymphatic system by Aureobasidium pullulans in a patient with erythema nodosum leprosum
Braz. j. infect. dis
;
15(3): 288-292, May-June 2011. ilus
Artigo
em Inglês
| LILACS
| ID: lil-589964
ABSTRACT
Aureobasidium pullulans is a causal agent of phaeohyphomycosis, occasionally found in men and animals. As an agent of different opportunistic fungal processes, it may cause fungemia, systemic infections and abscesses in different viscera. This paper aims to report a case of a patient with infection of the lymphatic system by A. pullulans. A 23-year-old patient being treated for erythema nodosum leprosum presented a 60-day complaint of daily fever, hoarseness, odynophagia and weight loss. Laboratory tests showed pancytopenia with severe neutropenia, cervical adenomegaly and solid contrast uptake lesion in the oropharyngeal region. Due to neutropenia and sepsis the patient was initially treated with cefepime and vancomycin, but there was no clinical improvement. Lymph node puncture-aspiration showed yeast-form fungus identified as A. pullulans by sequencing ITS region. The patient was treated with amphotericin B deoxycholate, leading to complete recovery of bone marrow function and regression of adenomegaly and the oropharyngeal lesion.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Ascomicetos
/
Hanseníase Virchowiana
/
Eritema Nodoso
/
Doenças Linfáticas
/
Micoses
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Braz. j. infect. dis
Assunto da revista:
Doenças Transmissíveis
Ano de publicação:
2011
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
UnB/BR
/
Universidade de Brasília/BR
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