On cytoadhesion of Plasmodium vivax: raison d'être?
Mem. Inst. Oswaldo Cruz
;
106(supl.1): 79-84, Aug. 2011. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-597247
ABSTRACT
It is generally accepted that Plasmodium vivax, the most widely distributed human malaria parasite, causes mild disease and that this species does not sequester in the deep capillaries of internal organs. Recent evidence, however, has demonstrated that there is severe disease, sometimes resulting in death, exclusively associated with P. vivax and that P. vivax-infected reticulocytes are able to cytoadhere in vitro to different endothelial cells and placental cryosections. Here, we review the scarce and preliminary data on cytoadherence in P. vivax, reinforcing the importance of this phenomenon in this species and highlighting the avenues that it opens for our understanding of the pathology of this neglected human malaria parasite.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Plasmodium vivax
/
Malária Vivax
/
Eritrócitos
Limite:
Humanos
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2011
Tipo de documento:
Artigo
País de afiliação:
Brasil
/
Espanha
Instituição/País de afiliação:
Fundação de Medicina Tropical Doutor Heitor Vieira/BR
/
Instituto Leônidas e Maria Deane-Fiocruz/BR
/
Universidade Estadual de Campinas/BR
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