Hypertriglyceridemia in a family with a high incidence of type II diabetes / Hipertrigliceridemia en una familia con una alta incidencia de diabetes tipo II
Invest. clín
;
28(4): 171-80, 1987. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-60132
ABSTRACT
Fourteen individuals from two generations of a familiy with a high incidence of type II diabetes were studied. Six out of twelve siblings (50%) developed diabetes between 24 and 45 years of age. They were the product of a non diabetic father, whose family had a high incidence of diabetes, and a diabetic mother (age of onset = 52 years) whose family history was negative for diabetes. The duration of diabetes in the siblings at the time of the study ranged from 3 to 13 years. Only one required insulin for control of hyperglycemia while the others were treated with oral hypoglycemic agents and/or diet. Hypertriglyceridemia was present ind 5 of the 6 diabetics sibligs (83%) and in several other non-diabetic members of the family and was highly correlated with age (r= 0.86; p< 0.01), but not with the body mass index or diet. It is proposed that a common genetic trait might account for both metabolic dysfunctions
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Índice:
LILACS (Américas)
Assunto principal:
Diabetes Mellitus
Tipo de estudo:
Estudo de incidência
/
Fatores de risco
/
Estudo de rastreamento
Limite:
Adulto
/
Humanos
Idioma:
Inglês
Revista:
Invest. clín
Assunto da revista:
Biologia
/
Medicina
/
Relatos de Casos
Ano de publicação:
1987
Tipo de documento:
Artigo
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