Circadian stage-dependent effect of acth and melatonin on protein synthesis by rat adrenal cells
Braz. j. med. biol. res
;
21(4): 759-62, 1988. tab
Artigo
em Inglês
| LILACS
| ID: lil-60777
ABSTRACT
The objective of the study was to determine the circadian effects of melatonin and two different ACTH preparations a synthetic heptadecapeptide with adrenocorticotrophic action (synchrodyn 1-17, HOE 433) and a natural ACTH (Acthar, Armour). Both ACTH preparations acted in a circadian stage-dependent fashion affecting the MESOR and the amplitude of total protein synthesis of rat adrenal cells. The results also indicated interaction of melatonin with the rhythmic action of ACTH. We conclude that circadian adrenocortical organization also modulates protein synthesis:
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LILACS (Américas)
Assunto principal:
Ritmo Circadiano
/
Glândulas Suprarrenais
/
Hormônio Adrenocorticotrópico
/
Melatonina
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1988
Tipo de documento:
Artigo
/
Congresso e conferência
/
Documento de projeto
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