Inflammatory edema induced by carrageenin in monosodium glutamate-treated rats
Braz. j. med. biol. res
;
21(4): 837-9, 1988. ilus
Artigo
em Inglês
| LILACS
| ID: lil-60802
RESUMO
Rats treated with monosodium glutamate (MSG) during the neonatal period show hypothalamic lesions and multiple neuroendocrine alterations manifested as a remarkable increase in levels of circulating corticosterone and obesity. Paw edema induced by local injection of carrageenin was significantly reduced in MSG-treated rats compared to normal rats. In contrast, both adrenalectomized rats and adrenalectomized, MSG-treated rats showed an increased response to carrageenin relative to controls. These results suggest that glucocorticoids are important modulators of inflammation in this phase of the process
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Índice:
LILACS (Américas)
Assunto principal:
Glutamato de Sódio
/
Carragenina
/
Edema
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1988
Tipo de documento:
Artigo
/
Congresso e conferência
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