Absence of mutagenicity of Potomorphe umbellata and Potomorphe peltata in the Salmonella/mammalian-microsome mutagenicity assay

ABSTRACT

The development of short term tests for measuring the mutagenic activity of genotoxic chemicals has been helpful in increasing security. Natural products from the flora are largely used in popular medicine. Using the Salmonella/mammalian-microsome assay, we investigated the genetic toxicity of two plant species popularly used in malaria treatment, Pothomorphe umbrellata and Pothomorphe peltata. The data show the absence of genetic toxicity for both plant species