El perímetro de la cintura como predictor de la secreción y sensibilidad insulínica en niñas chilenas con sobrepeso u obesidad / Waist circumference as a predictor of insulin secretion and sensibility in overweight and obese chilean girls
Rev. chil. endocrinol. diabetes
;
1(3): 164-169, jul. 2008. graf, tab
Artigo
em Espanhol
| LILACS
| ID: lil-612517
ABSTRACT
Abdominal fat, measured as waist circumference, is a risk factor for the development of metabolic andcardiovascular disorders. AIM:
To determine the association between anthropometric indicators and insulin resistance and secretion indexes. PATIENTS ANDMETHODS:
Cross sectional study of 51 girls aged 7 to 17 years, with a body mass index (BMI) > 85th percentile. Weight, height and waist circumference were measured. An oral glucose tolerance test was performed and fasting serum lipids were measured. Homeostasis model assessment of insulin resistance (HOMA-IR), Gutt´s Index (ISI0, 120), insulinogenic index (InIns) and the insulinogenic index corrected by HOMA-IR (InIns/HOMA-IR), were calculated.RESULTS:
A positive and significant correlation was found between waist circumference and Log HOMA-IR (R = 0,434, p < 0, 01) and a negative correlation with Log (InIns/HOMA-IR) (R = -0,463, p < 0,01). There was a weak correlation between BMI z score and Log (InIns/HOMA-IR) with a r= -0,285, p < 0,05. No association of BMI z score with other variables. After correcting for BMI z score, the association between waist circumference and Log HOMA-IR and Log (InIns/HOMA-IR) was maintained (R = 0,39, p = 0,015 and R = -0,43, p =0,006, respectively).CONCLUSIONS:
Among girls with with a BMI > 85 th percentile, waist circumference is the anthropometric variable that best correlates with insulin resistance and secretion indexes. We suggest incorporating the waist circumference measurement as a routine anthropometric variable during pediatric assessments.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Resistência à Insulina
/
Relação Cintura-Quadril
/
Sobrepeso
/
Obesidade
Tipo de estudo:
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adolescente
/
Criança
/
Feminino
/
Humanos
País/Região como assunto:
América do Sul
/
Chile
Idioma:
Espanhol
Revista:
Rev. chil. endocrinol. diabetes
Assunto da revista:
Endocrinologia
Ano de publicação:
2008
Tipo de documento:
Artigo
País de afiliação:
Chile
Instituição/País de afiliação:
Pontificia Universidad Católica de Chile/CL
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