Anticaries effect of dentifrices with calcium citrate and sodium trimetaphosphate
J. appl. oral sci
;
20(1): 94-98, Jan.-Feb. 2012. graf
Artigo
em Inglês
| LILACS
| ID: lil-618160
ABSTRACT
Because of the growing concerns regarding fluoride ingestion by young children and dental fluorosis, it is necessary to develop new dentifrices. OBJECTIVE: The aim of this study was to evaluate the effect of dentifrices with calcium citrate (Cacit) and sodium trimetaphosphate (TMP) on enamel demineralization. MATERIAL AND METHODS: Enamel blocks (n=70), previously selected through surface hardness analysis, were submitted to daily treatment with dentifrices diluted in artificial saliva and to a pH-cycling model. The fluoride concentration in dentifrices was 0, 250, 450, 550, 1,000 and 1,100 µg F/g. CrestTM was used as a positive control (1,100 mg F/g). Cacit (0.25 percent) and TMP (0.25 percent) were added to dentifrices with 450 and 1,000 µg F/g. Surface hardness was measured again and integrated loss of subsurface hardness and fluoride concentration in enamel were calculated. Parametric and correlation tests were used to determine difference (p<0.05) and dose-response relationship between treatments. RESULTS: The addition of Cacit and TMP did not provide a higher fluoride concentration in enamel, however it reduced (p<0.05) mineral loss when compared to other dentifrices; the dentifrice with Cacit and TMP and a low fluoride concentration presented similar results when compared to a dentifrice with 1,100 mg F/g (p>0.05). CONCLUSIONS: Dentifrices with 450 and 1,000 µg F/g, Cacit and TMP were as effective as a gold standard one.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Polifosfatos
/
Cariostáticos
/
Desmineralização do Dente
/
Citrato de Cálcio
/
Dentifrícios
/
Fluoretos
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudos de avaliação
Limite:
Humanos
Idioma:
Inglês
Revista:
J. appl. oral sci
Assunto da revista:
Odontologia
Ano de publicação:
2012
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Methodist University of Piracicaba/BR
/
State University of Campinas/BR
/
Univ. Estadual Paulista/BR
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