Utilidad de la medición de fructosamina como indicador de control en pacientes con diabetes gestacional y pregestacional / Plasma fructosamine to evaluate metabolic control among women with gestational diabetes
Rev. méd. Chile
;
139(11): 1444-1450, nov. 2011. ilus
Artigo
em Espanhol
| LILACS
| ID: lil-627574
ABSTRACT
Background:
Metabolic control of diabetic pregnant women is assessed using glycated hemoglobin (HbAlc) levels and fasting blood sugar. Another glycated protein, namely fructosamine, can be an indicator of average glucose levels during the last three weeks.Aim:
To evaluate plasma fructosamine as an indicator of glycemic control in women with gestational diabetes. Patients andMethods:
Prospective cohort study of 41 pregnant women aged 30 to 37 years, with gestational and pre-gestational diabetes. Blood glucose, HbAlc, fructosamine were measured. Newborn weight, and other prenatal and postnatal variables, were used to evaluate the correlation between metabolic control and the presence or absence of macrosomia.Results:
The correlation observed between fructosamine and fasting blood glucose (r = 0.627, p < 0.001) was superior to that of HbA1c and blood glucose (r = 0.516, p < 0.001). No association was observed between macrosomia and levels of fructosamine, nor between the other studied variables.Conclusions:
Fructosamine levels were not associated with macrosomia, but it could be better for the evaluation of glycemic control in patients with gestational diabetes since it allows short-term monitoring.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Glicemia
/
Macrossomia Fetal
/
Hemoglobinas Glicadas
/
Jejum
/
Diabetes Gestacional
/
Frutosamina
Tipo de estudo:
Estudo observacional
/
Fatores de risco
Limite:
Adulto
/
Feminino
/
Humanos
/
Gravidez
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2011
Tipo de documento:
Artigo
País de afiliação:
Chile
Instituição/País de afiliação:
Hospital Barros Luco Trudeau/CL
/
Hospital Eduardo Pereira/CL
/
Hospital de Mejillones/CL
/
Universidad de Valparaíso/CL
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