Wound-healing and benzodiazepines: does sleep play a role in this relationship?
Clinics
;
67(7): 827-830, July 2012. ilus
Artigo
em Inglês
| LILACS
| ID: lil-645458
ABSTRACT
Patients who have suffered burns frequently experience psychological consequences, among which anxiety disorders are prominent. Benzodiazepines are commonly administered to treat these symptoms. The effects of benzodiazepines on healing may not be direct but rather are modulated by alterations of the sleep architecture. This hypothesis is supported by studies that demonstrate the effects of benzodiazepines on the immune system and the inflammatory profile under both normal sleep conditions and during sleep deprivation, particularly rapid eye movement sleep deprivation.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Ansiolíticos
/
Cicatrização
/
Midazolam
/
Queimaduras
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Clinics
Assunto da revista:
Medicina
Ano de publicação:
2012
Tipo de documento:
Artigo
/
Documento de projeto
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Federal de São Paulo/BR
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