Effect of probiotic administration on the immune response: a systematic review of experimental models in rats
Braz. arch. biol. technol
;
55(5): 685-694, Sept.-Oct. 2012. tab
Artigo
em Inglês
| LILACS
| ID: lil-651651
ABSTRACT
The probiotic influence on the immune system, especially under pathogenic challenge conditions, still remains controversial. To address this, a systematic review of current studies concerning the efficacy of probiotics on the immune response of rats subjected to experimental challenges was conducted. The survey was conducted using PubMed, ISI Web of Science and Scielo databases. Only studies which tested probiotics in vivo in rats were included. The experimental design, methodological quality, and results of the articles were analyzed. In total 21 articles were selected for this study. The most commonly used microorganisms in the experiments were those of the genus Lactobacillus, which was reported in 12 articles. The second most often used genus was Bifidobacterium (B. animalis and B.longum). In general, the probiotics use against experimental pathogenic challenges was successful 86% of the selected articles reported a beneficial effect on the immune response associated with the use of probiotics.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Tipo de estudo:
Revisões Sistemáticas Avaliadas
Idioma:
Inglês
Revista:
Braz. arch. biol. technol
Assunto da revista:
Biologia
Ano de publicação:
2012
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Federal de Lavras/BR
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