Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in rats
Acta cir. bras
;
28(2): 94-101, Feb. 2013. ilus, graf, tab
Artigo
em Inglês
| LILACS
| ID: lil-662355
ABSTRACT
PURPOSE:
To compare the degree of neural regeneration in rats upon interposition of autologous nerve graft, autogenous vein, glycerol-preserved autogenous vein, and glycerol-preserved allogeneic vein using qualitative and quantitative histological analyses as well as functional assessments.METHODS:
Peroneal nerves were reconstructed differently in four groups of animals. Functional assessments were performed pre- and postoperatively for a period of six weeks. After six weeks, the animals were sacrificed and histological evaluations were performed.RESULTS:
Histological patterns of autogenous veins without preservation showed pronounced neoangiogenesis and extensive axonal rarefaction, as confirmed by axonal counting and functional assessments. Glycerol-preserved veins had results similar to the control.CONCLUSIONS:
Glycerol-preserved autogenous or allogeneic veins showed similar results to autograft results. The autogenous vein (without preservation in glycerol) presented histological and functional outcomes statistically lower than other groups.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Nervo Fibular
/
Preservação de Tecido
/
Glicerol
/
Veias Jugulares
/
Regeneração Nervosa
Tipo de estudo:
Pesquisa qualitativa
Limite:
Animais
Idioma:
Inglês
Revista:
Acta cir. bras
Assunto da revista:
Cirurgia Geral
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2013
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
USP/BR
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