Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam
Acta cir. bras
;
28(3): 185-189, Mar. 2013. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-667928
ABSTRACT
PURPOSE:
To investigate the immunohistochemistry of the uterine cervix of 20 Wistar rats (Rattus norvegicus) bearing the Walker 256 tumor, treated with copaiba oil (Copaifera officinalis).METHODS:
The animals were grouped into four subgroups, with five rats each the GCT and GCopT received distilled water and topically copaiba, respectively, while the GCG and GCopG received distilled water and copaiba by gavage, respectively. The substances were administered for nine days. On the 12th day, after euthanasia, the tumor pieces were sent to the identification of T CD4+, T CD8+ and Natural Killer cells.RESULTS:
It was found that the pattern of expression for specific markers of phenotypes of cells involved in tumor immune response was similar in all groups, regardless the administration way of copaiba oil (topical or gavage).CONCLUSION:
Copaiba balsam, administered either topically or by gavage, did not alter the pattern of tumor immune response in rats bearing Walker 256 Tumor.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Bálsamos
/
Colo do Útero
/
Antineoplásicos Fitogênicos
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
Idioma:
Inglês
Revista:
Acta cir. bras
Assunto da revista:
Cirurgia Geral
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2013
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
UEPA/BR
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