Analysis of batch and repeated fedbatch productions of Candida utilis cell mass using mathematical modeling method
Electron. j. biotechnol
;
16(4): 2-2, July 2013. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-684017
ABSTRACT
Background:
Candida utilis is widely used in bioindustry, and its cell mass needs to be produced in a cost effective way. Process optimization based on the experimental results is the major way to reduce the production cost. However, this process is expensive, time consuming and labor intensive. Mathematical modeling is a useful tool for process analysis and optimization. Furthermore, sufficient information can be obtained with fewer experiments by using the mathematical modeling, and some results can be predicted even without doing experiments.Results:
In the present study, we performed the mathematical modeling and simulation for the cell mass production of Candida utilis based on limited batch and repeated fedbatch experiments. The model parameters were optimized using genetic algorithm (GA), and the processes were analyzed.Conclusions:
Taken together, this newly developed method is efficient, labor saving and cost effective.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Candida
/
Modelos Teóricos
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Revista:
Electron. j. biotechnol
Assunto da revista:
Biotecnologia
Ano de publicação:
2013
Tipo de documento:
Artigo
País de afiliação:
China
Instituição/País de afiliação:
Zhejiang University/CN
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