Experimental model for the study of soft tissue fixation methods on skin-pericranium flaps in rats
Acta cir. bras
;
28(10): 696-702, Oct. 2013. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-687742
ABSTRACT
PURPOSE:
To develop an experimental model to study and radiologically monitor displacement of skin flaps in the pericranium of rats subjected to traction and surgical fixation using suture anchored in a skull bone tunnel or with N-butyl-2-cyanoacrylate (HistoacrylTM) surgical adhesive.METHODS:
Radiological markers were placed in the subcutis of Wistar rats undergoing subperiosteal detachment of the pericranium with pulling and fixation of the flap. We performed radiography on postoperative days 3, 7, 14, 21, and 45. A p-value of <0.05 was considered significant.RESULTS:
Qualitative analysis of the data indicated that the flaps in the surgical adhesive group remained in place with no change from the immediate postoperative position. However, the flaps in the suture anchored in the skull bone tunnel group and in the control group showed similar healing, with a loss of attachment of 9.7% and 22%, respectively, compared with the immediate postoperative position. There was no quantitative difference between the groups.CONCLUSIONS:
This experimental model created acceptable experimental conditions for testing different soft tissue fixation methods. The use of tissue fixatives contributed to better placement of pericranium-cutaneous flaps, and surgical adhesive was superior to suture anchor in the skull bone tunnel for fixation of pericranium-cutaneous flaps.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Crânio
/
Retalhos Cirúrgicos
/
Adesivos Teciduais
/
Cicatrização
/
Fixação de Tecidos
/
Modelos Animais
Tipo de estudo:
Estudo prognóstico
/
Pesquisa qualitativa
Limite:
Animais
Idioma:
Inglês
Revista:
Acta cir. bras
Assunto da revista:
Cirurgia Geral
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2013
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
State University of Campinas/BR
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