Essential thrombocythemia: a rare disease in childhood
Rev. bras. hematol. hemoter
;
35(4): 287-289, 2013. tab
Artigo
em Inglês
| LILACS
| ID: lil-687926
ABSTRACT
Essential thrombocythemia is an acquired myeloproliferative disorder characterized by the proliferation of megakaryocytes in bone marrow, leading to a persistent increase in the number of circulating platelets and thus increasing the risk for thrombotic and hemorrhagic events. The disease features leukocytosis, splenomegaly, vascular occlusive events, hemorrhages and vasomotor disorders. The intricate mechanisms underlying the molecular pathogenesis of this disorder are not completely understood and are still a matter of discussion. Essential thrombocythemia is an extremely rare disorder during childhood. We report on a case of essential thrombocythemia in a child and discuss the diagnostic approach and treatment strategy.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Bancos de Sangue
/
Doadores de Sangue
/
Distribuição Temporal
Limite:
Humanos
Idioma:
Inglês
Revista:
Rev. bras. hematol. hemoter
Assunto da revista:
Hematologia
Ano de publicação:
2013
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade de São Paulo/BR
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