Modulation of cerebral malaria by curcumin as an adjunctive therapy
Braz. j. infect. dis
;
17(5): 579-591, Sept.-Oct. 2013. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-689884
ABSTRACT
Cerebral malaria is the most severe and rapidly fatal neurological complication of Plasmodium falciparum infection and responsible for more than two million deaths annually. The current therapy is inadequate in terms of reducing mortality or post-treatment symptoms such as neurological and cognitive deficits. The pathophysiology of cerebral malaria is quite complex and offers a variety of targets which remain to be exploited for better therapeutic outcome. The present review discusses on the pathophysiology of cerebral malaria with particular emphasis on scope and promises of curcumin as an adjunctive therapy to improve survival and overcome neurological deficits.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Adjuvantes Farmacêuticos
/
Malária Cerebral
/
Curcumina
/
Antimaláricos
Limite:
Humanos
Idioma:
Inglês
Revista:
Braz. j. infect. dis
Assunto da revista:
Doenças Transmissíveis
Ano de publicação:
2013
Tipo de documento:
Artigo
País de afiliação:
Índia
Instituição/País de afiliação:
J.S.S. College of Pharmacy/IN
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