Animal models of neurodegenerative diseases
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
35(supl.2): S82-S91, 2013. graf
Artigo
em Inglês
| LILACS
| ID: lil-691406
ABSTRACT
The prevalence of neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD), increases with age, and the number of affected patients is expected to increase worldwide in the next decades. Accurately understanding the etiopathogenic mechanisms of these diseases is a crucial step for developing disease-modifying drugs able to preclude their emergence or at least slow their progression. Animal models contribute to increase the knowledge on the pathophysiology of neurodegenerative diseases. These models reproduce different aspects of a given disease, as well as the histopathological lesions and its main symptoms. The purpose of this review is to present the main animal models for AD, PD, and Huntington's disease.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Doença de Parkinson
/
Doença de Huntington
/
Modelos Animais de Doenças
/
Doença de Alzheimer
Tipo de estudo:
Fatores de risco
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Assunto da revista:
Psiquiatria
Ano de publicação:
2013
Tipo de documento:
Artigo
/
Documento de projeto
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Federal de Minas Gerais/BR
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