Cytological changes in oral epithelium due to Sudanese homemade alcoholic beverages
RSBO (Impr.)
;
10(1): 34-39, Jan.-Mar. 2013. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-695910
ABSTRACT
Introduction and Objective:
The aim of this study was to assess the cytological changes in oral epithelium that might be induced by Sudanese homemade alcoholic beverages. Material andmethods:
Oral Exfoliative Cytology (OEFC) was applied to a case control study to assess the presence and severity of oral epithelial atypia (ET) in 300 subjects (150 alcohol abuse individuals (cases); 150 non-alcohol abuse individuals (controls)). All cases were using homemade alcoholic drinks, locally known as, Aragee, Marisa and others. Five patients with oral squamous cell carcinoma (OSCCs) were included as internal controls.Results:
ET was detected in 7 subjects and was not observed in the remaining 293. All the 7 subjects with cytological atypia were cases. Cytological atypia were identified among those using Aragee, Marisa, and Aragee & Marisa together, representing 53%, 28.6%, 18%.4, respectively. Cytological atypia was found in all the 5 control cases with OSCCs. For the cytological atypia among alcohol abuse individuals, the adjusted OR and the 95% CI were found to be 5 (4.34-5.84) and P = 0.008. Inflammatory cells infiltrates were identified among 21 (14%) of the cases and only 12 (8%) of the controls and the adjusted OR and the 95% CI were found to be 5 (2.51-11.21) and P = 0.009.Conclusion:
In view of these findings, Sudanese homemade alcoholic beverages cause oral epithelial atypical changes, which lead to oral precancerous and cancerous lesions. OEFC is a useful procedure for detection and assessment of oral ET.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Idioma:
Inglês
Revista:
RSBO (Impr.)
Assunto da revista:
Odontologia
Ano de publicação:
2013
Tipo de documento:
Artigo
País de afiliação:
Sudão
Instituição/País de afiliação:
University of Khartoum/SD
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