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Insights from paleomicrobiology into the indigenous peoples of pre-colonial America - A Review
Darling, Millie I; Donoghue, Helen D.
  • Darling, Millie I; University College London. Centre for Clinical Microbiology. Division of Biosciences. London. GB
  • Donoghue, Helen D; University College London. Centre for Clinical Microbiology. Division of Biosciences. London. GB
Mem. Inst. Oswaldo Cruz ; 109(2): 131-139, abr. 2014.
Artigo em Inglês | LILACS | ID: lil-705820
ABSTRACT
This review investigates ancient infectious diseases in the Americas dated to the pre-colonial period and considers what these findings can tell us about the history of the indigenous peoples of the Americas. It gives an overview, but focuses on four microbial pathogens from this period Helicobacter pylori, Mycobacterium tuberculosis, Trypanosoma cruzi and Coccidioides immitis, which cause stomach ulceration and gastric cancer, tuberculosis, Chagas disease and valley fever, respectively. These pathogens were selected as H. pylori can give insight into ancient human migrations into the Americas, M. tuberculosis is associated with population density and urban development, T. cruzi can elucidate human living conditions and C. immitis can indicate agricultural development. A range of methods are used to diagnose infectious disease in ancient human remains, with DNA analysis by polymerase chain reaction one of the most reliable, provided strict precautions are taken against cross contamination. The review concludes with a brief summary of the changes that took place after European exploration and colonisation.
Assuntos


Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: DNA Bacteriano / DNA de Protozoário / Grupos Populacionais Tipo de estudo: Estudo diagnóstico Limite: Humanos Idioma: Inglês Revista: Mem. Inst. Oswaldo Cruz Assunto da revista: Medicina Tropical / Parasitologia Ano de publicação: 2014 Tipo de documento: Artigo País de afiliação: Reino Unido Instituição/País de afiliação: University College London/GB

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Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: DNA Bacteriano / DNA de Protozoário / Grupos Populacionais Tipo de estudo: Estudo diagnóstico Limite: Humanos Idioma: Inglês Revista: Mem. Inst. Oswaldo Cruz Assunto da revista: Medicina Tropical / Parasitologia Ano de publicação: 2014 Tipo de documento: Artigo País de afiliação: Reino Unido Instituição/País de afiliação: University College London/GB