Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate
Acta cir. bras
;
29(4): 274-279, abr. 2014. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-706955
ABSTRACT
To evaluate the effect of diabetes mellitus and of sildenafil citrate on female urethral function. Twenty nine female rats were divided into four groups: G1 - (n=9), normal rats; G2 - (n=6), normal rats treated with sildenafil citrate; G3 - (n=9) rats with alloxan-induced diabetes; G4 - (n=5) rats with alloxan-induced diabetes treated with sildenafil citrate. Under anesthesia, urodynamic evaluation was performed by cystometry and urethral pressure simultaneously. A significant increase in urethral pressure was observed during micturition. Sildenafil citrate can partially reduced urethral pressure in diabetic female rats.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Uretra
/
Bexiga Urinária
/
Alloxanum
/
Complicações do Diabetes
Limite:
Animais
Idioma:
Inglês
Revista:
Acta cir. bras
Assunto da revista:
Cirurgia Geral
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2014
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade de São Paulo/BR
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