The use of botulinum toxin type A in the treatment of HTLV-1-associated overactive bladder refractory to conventional therapy
Rev. Soc. Bras. Med. Trop
;
47(4): 528-532, Jul-Aug/2014. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-722305
ABSTRACT
Urinary symptoms occur in 19% of human T-cell lymphotropic virus type 1 (HTLV-1)-infected patients who do not fulfill criteria for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and in almost 100% of HAM/TSP patients. Few studies have evaluated therapies for overactive bladder (OAB) caused by HTLV-1 infection. This case report describes the effect of onabotulinum toxin A on the urinary manifestations of three patients with HAM/TSP and OAB symptoms. The patients were intravesically administered 200 units of Botox®. Their incontinence episodes improved, and their OAB symptoms scores (OABSS) reduced significantly. These data indicate that Botox® should be a treatment option for OAB associated with HTLV-1 infection.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Paraparesia Espástica Tropical
/
Toxinas Botulínicas Tipo A
/
Bexiga Urinária Hiperativa
/
Inibidores da Liberação da Acetilcolina
Tipo de estudo:
Fatores de risco
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2014
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Federal da Bahia/BR
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