Fibrosis retroperitoneal asociada a neoplasias malignas: Serie de casos clínicos / Retroperitoneal fibrosis associated with malignancies: Report of eight cases
Rev. méd. Chile
;
142(6): 791-798, jun. 2014. ilus, tab
Artigo
em Espanhol
| LILACS
| ID: lil-722930
ABSTRACT
Retroperitoneal fibrosis (RPF) is uncommon. Eight percent of cases are associated with malignancies. The pathogenesis of cancer related RPF (MRPF) is unknown. It may be originated from a desmoplastic reaction of the retroperitoneum to the presence of malignant cells, to the action of cytokines secreted by the tumor or a reactive inflammation. MRPF may also be a consequence of antineoplastic therapy (surgery, radiotherapy and chemotherapy). We report eight cases of MRPF associated with breast, cervix, thyroid, kidney and retroperitoneal cancer. In four patients, retroperitoneal tissue biopsy was performed, showing the typical findings of idiopathic RPF. In 6 patients MRPF appeared one to 15 years after cancer diagnosis and in two, it appeared simultaneously. The clinical presentation, course and therapeutic response are described. Six patients were treated with steroids alone and five with steroids associated with colchicine.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Fibrose Retroperitoneal
/
Neoplasias
Tipo de estudo:
Estudo diagnóstico
/
Fatores de risco
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2014
Tipo de documento:
Artigo
País de afiliação:
Chile
Instituição/País de afiliação:
Universidad de Valparaíso/CL
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