Prevalence of high-risk human papillomavirus by cobas 4800 HPV test in urban Peru
Braz. j. infect. dis
;
18(5): 469-472, Sep-Oct/2014. tab
Artigo
em Inglês
| LILACS
| ID: lil-723088
ABSTRACT
Background:
Molecular tests allow the detection of high-risk human papillomavirus in cervical samples, playing an important role in the prevention of cervical cancer.Objectives:
We performed a study to determine the prevalence of HPV 16, HPV 18 and other high-risk human papillomavirus (pool 12 genotypes) in Peruvian females from diverse urban areas using the cobas 4800 HPV test.Methods:
Routine cervical samples collected in our laboratory were analyzed by cobas 4800 HPV test.Results:
A total of 2247 samples from female patients aged 17–79 years were tested. high-risk human papillomavirus was positive in 775 (34.49%) samples. Of these, 641 (82.71%) were single infections and 134 (17.29%) were multiple infections. The positivity rates for HPV 16, HPV 18, and other high-risk human papillomavirus were 10.77%, 2.0%, and 28.08%, respectively. In multiple high-risk human papillomavirus infections, the concomitance of HPV 16 and other high-risk human papillomavirus was more prevalent (13.42%).Conclusion:
Our study showed high prevalence of high-risk human papillomavirus in urban Peru, mainly among young women. In both single and multiple infections other high-risk human papillomavirus were more prevalent than HPV 16 and HPV 18, which might influence vaccine impact in our country. Furthermore, the cobas 4800 HPV test may be considered a useful tool for HPV molecular diagnosis. .
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Colo do Útero
/
Infecções por Papillomavirus
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
/
Estudo de prevalência
/
Fatores de risco
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
País/Região como assunto:
América do Sul
/
Peru
Idioma:
Inglês
Revista:
Braz. j. infect. dis
Assunto da revista:
Doenças Transmissíveis
Ano de publicação:
2014
Tipo de documento:
Artigo
País de afiliação:
Peru
Instituição/País de afiliação:
Precisa Laboratorios Arias Stella/PE
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