Analysis of the repair of bone defects filled with ß-tricalcium phosphate associated to pure titanium implants / Análise do reparo de defeitos ósseos preenchidos com ß-Tricálcio Fosfato associado a implantes de titânio

ABSTRACT

Objective: The present study aims to develop a histolo-gical descriptive analysis on the repair of bone defects filled with ?-TCP, associated to pure titanium implants into cavities prepared in the calvarial bone of rats. Ma-terials and method: Eighteen male adult rats were ran-domly selected and divided into three groups of six rats each, according to their period of death: 15, 30, and 60 days. Four bone defects were made into each one of the calvarial bones of rats and filled with: (a) ?-TCP, (b) clot, (c) ?-TCP + pure titanium screw, and (d) pure titanium screw. The samples were cut and histologically assessed. Presence and volume of loose connective tis-sue and newly formed bone tissue were analyzed, as well as the presence or absence of remaining material (?-TCP) into the defect. Results: It was verified an acce-leration bone neoformation process in the presence of ?-TCP. Conclusion: The results suggest the biocompa-tibility and osteoconductivity of the biomaterial, even when associated to pure titanium implants.