Evaluation of the role of ATP-binding cassette transporters as a defence mechanism against temephos in populations of Aedes aegypti
Mem. Inst. Oswaldo Cruz
;
109(7): 964-966, 11/2014. tab
Artigo
em Inglês
| LILACS
| ID: lil-728807
ABSTRACT
The role of ATP-binding cassette (ABC) transporters in the efflux of the insecticide, temephos, was assessed in the larvae of Aedes aegypti. Bioassays were conducted using mosquito populations that were either susceptible or resistant to temephos by exposure to insecticide alone or in combination with sublethal doses of the ABC transporter inhibitor, verapamil (30, 35 and 40 μM). The best result in the series was obtained with the addition of verapamil (40 μM), which led to a 2x increase in the toxicity of temephos, suggesting that ABC transporters may be partially involved in conferring resistance to the populations evaluated.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Temefós
/
Resistência a Inseticidas
/
Transportadores de Cassetes de Ligação de ATP
/
Aedes
/
Insetos Vetores
/
Inseticidas
Limite:
Animais
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2014
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Federal do Cariri/BR
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