Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region
Mem. Inst. Oswaldo Cruz
;
110(1): 151-153, 03/02/2015. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-741612
ABSTRACT
The Brazilian Amazon Region is a highly endemic area for hepatitis B virus (HBV). However, little is known regarding the genetic variability of the strains circulating in this geographical region. Here, we describe the first full-length genomes of HBV isolated in the Brazilian Amazon Region; these genomes are also the first complete HBV subgenotype D3 genomes reported for Brazil. The genomes of the five Brazilian isolates were all 3,182 base pairs in length and the isolates were classified as belonging to subgenotype D3, subtypes ayw2 (n = 3) and ayw3 (n = 2). Phylogenetic analysis suggested that the Brazilian sequences are not likely to be closely related to European D3 sequences. Such results will contribute to further epidemiological and evolutionary studies of HBV.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Transdução de Sinais
/
Movimento Celular
/
Carcinoma Hepatocelular
/
Inibidor Tecidual de Metaloproteinase-1
/
Metaloproteinase 9 da Matriz
/
Neoplasias Hepáticas
Limite:
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2015
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Fiocruz/BR
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