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Effect of high-voltage electrical stimulation on the albumin and histamine serum concentrations, edema, and pain in acute joint inflammation of rats
Sandoval, Maria C; Ramirez, Carolina R; Camargo, Diana M; Russo, Thiago L; Salvini, Tania F.
  • Sandoval, Maria C; Universidade Industrial de Santander. Escola de Fisioterapia. Bucaramanga. CO
  • Ramirez, Carolina R; Universidade Industrial de Santander. Escola de Fisioterapia. Bucaramanga. CO
  • Camargo, Diana M; Universidade Industrial de Santander. Escola de Fisioterapia. Bucaramanga. CO
  • Russo, Thiago L; Universidade Industrial de Santander. Escola de Fisioterapia. Bucaramanga. CO
  • Salvini, Tania F; Universidade Industrial de Santander. Escola de Fisioterapia. Bucaramanga. CO
Braz. j. phys. ther. (Impr.) ; 19(2): 89-96, 27/04/2015. tab
Artigo em Inglês | LILACS | ID: lil-745808
ABSTRACT

BACKGROUND:

The mechanism by which high-voltage electrical stimulation (HVPC) acts on edema reduction is unknown.

OBJECTIVE:

To assess the effect of HVPC with negative polarity (-) applied to the ankle of rats with acute joint inflammation.

METHOD:

Sixty-four rats were divided into four groups (n=16) inflamed+HVPC(-), 0.03 mL application of ι-carrageenan (3%) to the tibiotarsal joint plus HVPC(-); inflamed+HVPC placebo, carrageenan application and HVPC placebo; normal+HVPC(-), HVPC application(-); and normal control, no intervention. The HVPC(-) 100 Hz at a submotor level was applied daily for 45 min on three consecutive days. The variables were pain, hind-foot volume, and serum histamine and albumin assessed before and during the 48 hours following inflammation. The variables were compared using the t test, one-way ANOVA, nested ANOVA for repeated measures, and the post hoc Bonferroni test. Analysis of covariance was applied to adjust the effects of HVPC(-) by measurements of pain, inflammation, albumin, and histamine at 24 h, and the final weight was compared to the other groups. The significance level was set at p<0.05.

RESULTS:

There were no differences between the inflamed+HVPC(-) and inflamed+HVPC placebo groups in terms of pain or edema (p>0.05). Albumin was reduced in the groups that received the intervention, but there was no differences between them. There was only a 24 hour increase in histamine with the normal+HVPC(-) (p=0.0001) and inflamed+HVPC placebo groups (p=0.01) compared to the normal control group.

CONCLUSIONS:

The results of the present study suggest that HVPC(-) with the parameters employed did not reduce pain or edema and did not change serum albumin or histamine levels,, which indicates the inability of this resource to have a positive effect when treating treat acute joint inflammation. .
Assuntos


Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Dor / Artrite / Albumina Sérica / Histamina / Terapia por Estimulação Elétrica / Edema Tipo de estudo: Estudo de etiologia Limite: Animais Idioma: Inglês Revista: Braz. j. phys. ther. (Impr.) Assunto da revista: MEDICINA FISICA E REABILITACAO Ano de publicação: 2015 Tipo de documento: Artigo País de afiliação: Colômbia Instituição/País de afiliação: Universidade Industrial de Santander/CO

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Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Dor / Artrite / Albumina Sérica / Histamina / Terapia por Estimulação Elétrica / Edema Tipo de estudo: Estudo de etiologia Limite: Animais Idioma: Inglês Revista: Braz. j. phys. ther. (Impr.) Assunto da revista: MEDICINA FISICA E REABILITACAO Ano de publicação: 2015 Tipo de documento: Artigo País de afiliação: Colômbia Instituição/País de afiliação: Universidade Industrial de Santander/CO