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Use of biological Glue (Bioglue®) in laparoscopic partial nephrectomy: a study in pigs
Brandão, Luis Felipe; Torricelli, Fabio Cesar Miranda; Melo, Glauco; Takano, Luiz Fernando; Mitre, Anuar Ibrahim; Arap, Marco Antonio.
Afiliação
  • Brandão, Luis Felipe; Hospital Sirio Libanes. Instituto de Ensino e Pesquisa. Sao Paulo. BR
  • Torricelli, Fabio Cesar Miranda; Hospital Sirio Libanes. Instituto de Ensino e Pesquisa. Sao Paulo. BR
  • Melo, Glauco; Hospital Sirio Libanes. Instituto de Ensino e Pesquisa. Sao Paulo. BR
  • Takano, Luiz Fernando; Hospital Sirio Libanes. Instituto de Ensino e Pesquisa. Sao Paulo. BR
  • Mitre, Anuar Ibrahim; Hospital Sirio Libanes. Instituto de Ensino e Pesquisa. Sao Paulo. BR
  • Arap, Marco Antonio; Hospital Sirio Libanes. Instituto de Ensino e Pesquisa. Sao Paulo. BR
Int. braz. j. urol ; 41(2): 252-257, Mar-Apr/2015. tab, graf
Article em En | LILACS | ID: lil-748282
Biblioteca responsável: BR1.1
ABSTRACT
Introduction Partial nephrectomy is the standard of care for localized renal tumors. However, bleeding and warm ischemia time are still controversial when laparoscopic surgeries are carried out. Herein, we aim to compare the outcomes from laparoscopic partial nephrectomy with and without the use of biological glue with purified bovine albumin and glutaraldehyde (BioGlue®). Materials and Methods Twenty-four kidneys of 12 pigs were used in this study. A pre-determined lower pole segment was resected (3 cm x 1 cm) and one of two different hemostatic techniques was performed. In one kidney, hemostatic “U suture” (poliglecaprone 3.0) was performed and in the contra-lateral kidney, only the biological glue was applied. Data recorded was comprised of warm ischemia time (seconds) and estimated blood loss (mL) for each procedure. In cases of bleeding after glue administration, a complementary suture was done. Results Mean warm ischemia time was 492.9±113.1 (351-665) seconds and 746±185.3 (409-1125) seconds for biological glue and suture groups, respectively. There was a positive significant difference in terms of warm ischemia favoring the biological glue group over the suture group (p<0.001). Mean blood loss was 39.4 (0-115) mL for the biological glue group and 39.1 (5-120) mL for the suture group (p=0.62). Conclusion Biological glue is an important tool for laparoscopic partial nephrectomies. It is effective for hemostatic control in selected cases, and it can be used in combination with the traditional suture techniques. .
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Texto completo: 1 Índice: LILACS Assunto principal: Demência Vascular Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Int. braz. j. urol Assunto da revista: UROLOGIA Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Índice: LILACS Assunto principal: Demência Vascular Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Int. braz. j. urol Assunto da revista: UROLOGIA Ano de publicação: 2015 Tipo de documento: Article