Azathioprine-induced accelerated cutaneous and pulmonary nodulosis in a patient with rheumatoid arthritis
An. bras. dermatol
;
90(3,supl.1): 162-164, May-June 2015. ilus
Artigo
em Inglês
| LILACS
| ID: lil-755763
ABSTRACT
We report the case of a 42-year-old female with a 5-year history of rheumatoid arthritis treated with Rituximab and Azathioprine. Three months after the initiation of Azathioprine, the patient started with dry cough and noted the rapid development of multiple subcutaneous nodules on her right leg. CT scan of the chest demonstrates pulmonary nodulosis. Skin biopsy was compatible with rheumatoid nodule. A diagnosis of "accelerated cutaneous and pulmonary nodulosis" was considered. Azathioprine was discontinued and Rituximab was restarted. Two months later, most of the subcutaneous nodules had disappeared. This is the second case report of accelerated rheumatoid nodulosis in association with Azathioprine treatment.
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Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Artrite Reumatoide
/
Nódulo Reumatoide
/
Azatioprina
/
Antirreumáticos
/
Nódulos Pulmonares Múltiplos
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
An. bras. dermatol
Assunto da revista:
Dermatologia
Ano de publicação:
2015
Tipo de documento:
Artigo
País de afiliação:
Chile
Instituição/País de afiliação:
Pontificia Universidad Catolica de Chile/CL
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