Orbitopatía de Graves en pediatría / Graves orbitopathy in pediatrics
Rev. méd. Chile
;
143(8): 1034-1041, ago. 2015. tab
Artigo
em Espanhol
| LILACS
| ID: lil-762670
ABSTRACT
Graves orbitopathy (GO) is rare in pediatric patients, however is the most common extrathyroid manifestation of Graves disease (GD), being present in 30-67% of patients. GO is an autoimmune inflammatory disorder involving orbital connective and fatty tissues as well as the extraocular muscles. In children, GO is less common and less severe than in adults. The most common symptoms are upper eyelid retraction, conjunctival injection, and proptosis and periorbital edema. Severe complications include dysthyroid optic neuropathy, corneal ulceration and eyeball subluxation. The diagnosis is established by clinical, laboratory and imaging findings. There are no management guidelines for GO in children but adult recommendations include the assessment of clinical activity and its severity, to implement the best treatment. Supportive therapies are intended to relieve symptoms and prevent corneal damage in mild cases. Tobacco exposure should also be avoided. The first line of treatment is systemic administration of corticosteroids in active and severe cases. Other options as somatostatin use and retrobulbar radiation have not been used in children, therefore their use is not recommended.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Oftalmopatia de Graves
Tipo de estudo:
Estudo de etiologia
/
Guia de Prática Clínica
Limite:
Adolescente
/
Criança
/
Humanos
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2015
Tipo de documento:
Artigo
País de afiliação:
Chile
Instituição/País de afiliação:
Pontificia Universidad Catolica de Chile/CL
Similares
MEDLINE
...
LILACS
LIS