The effects of ankaferd blood stopper and microporous polysaccharide hemospheres on epidural fibrosis in rat laminectomy model
Acta cir. bras
;
30(12): 799-805, Dec. 2015. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-769507
ABSTRACT
ABSTRACT PURPOSE:
To investigate whether topically administered hemostatic agents ankaferd blood stopper and microporous polysaccharide hemospheres can decrease epidural fibrosis after laminectomy in rats.METHODS:
Eighteen adult male Sprague-Dawley rats were equally and randomly divided into three groups. In the treatment groups, ankaferd blood stopper and microporous polysaccharide hemospheres topically administrated upon duramater surface after laminectomy. Fibroblast count, epidural fibrosis and arachnoidal involvement were evaluated and graded histopathologically.RESULTS:
Our data revealed that the count of fibroblasts, the grading of epidural fibrosis and arachnoideal involvement in the rats treated with microporous polysaccharide hemospheres were significantly less than the control group. Although the arachnoideal involvement in ankaferd blood stopper group were significantly less than the control group, there were no statistical differences when comparing the grading of epidural fibrosis and the fibroblasts count between the treatment groups and the control group.CONCLUSION:
The ankaferd blood stopper and microporous polysaccharide hemospheres reduced epidural fibrosis and arachnoideal involvement after laminectomy in rats.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Polissacarídeos
/
Complicações Pós-Operatórias
/
Hemostáticos
/
Extratos Vegetais
/
Espaço Epidural
Limite:
Animais
Idioma:
Inglês
Revista:
Acta cir. bras
Assunto da revista:
Cirurgia Geral
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2015
Tipo de documento:
Artigo
País de afiliação:
Turquia
Instituição/País de afiliação:
Ministry of Health Diskapi Yildirim Beyazit Training and Research Hospital/TR
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