Glucose release by the liver under conditions of reduced activity of glucose 6-phosphatase
Braz. j. med. biol. res
; 20(6): 837-43, 1987. ilus
Article
em En
| LILACS
| ID: lil-77464
Biblioteca responsável:
BR26.1
ABSTRACT
An inhibitor of glucose 6-phosphatase, isosteviol, was used in liver perfusion experiments to obtain a rough estimate of the control strength of the enzyme. Isosteviol only inhibited glucose release at high concentrations (1 mM), well above that needed for half-maximal action (70 micrnM). The decrease in glucose release was followed by an increase in the intracellular glucose 6-phosphate concentration. It was concluded that the control strength of glucose-6-phosphatase is relatively low
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Índice:
LILACS
Assunto principal:
Diterpenos
/
Glucose
/
Glucofosfatos
/
Fígado
Limite:
Animals
Idioma:
En
Revista:
Braz. j. med. biol. res
Assunto da revista:
BIOLOGIA
/
MEDICINA
Ano de publicação:
1987
Tipo de documento:
Article
/
Congress and conference