Ateroesclerosis subclínica en población de riesgo cardiovascular bajo y moderado por Framingham chileno / Subclinical atherosclerosis among Chilean subjects classified as having a low cardiovascular Framingham risk
Rev. méd. Chile
;
144(1): 30-38, ene. 2016. graf, tab
Artigo
em Espanhol
| LILACS
| ID: lil-776972
ABSTRACT
Background:
Framingham risk score (FRS) has limitations and can underestimate risk. Carotid ultrasound to measure intima media thickness or plaques is recommended for cardiovascular risk assessment.Aim:
To determine the prevalence of subclinical atherosclerosis in asymptomatic subjects classified as low and intermediate risk. Material andMethods:
Cross-sectional study performed in subjects without cardiovascular disease. Cardiovascular risk was estimated using the Chilean FRS and the General Cardiovascular Disease FRS. Carotid ultrasound was performed in all subjects. We defined subclinical atherosclerosis as the presence of carotid plaque or intima media thickness greater than 75th percentile by gender and age.Results:
We studied 203 subjects aged 47.2 ± 9.6 years (54% males). Mean intima media thickness was 0.62 ± 0.1 mm. An abnormal value was detected in 68 subjects (33%) and carotid plaques in 32 subjects (15.7%). Based on Chilean FRS, 96% were considered at low risk, 4% at intermediate, and none at high risk. In the low risk group the prevalence of abnormal intima media thickness and plaques was 40 and 14% respectively. Presence of plaques was more common in women than men (23 and 7% respectively, p < 0.01). According to the General Cardiovascular Disease FRS, 23% were at low, 39% at low intermediate and 28% at high intermediate risk. In the low risk group the prevalence of an abnormal intima media thickness was 34% and no subject had plaques.Conclusions:
Carotid plaques were detected in Chilean subjects classified as having a low FRS risk. The underestimation of risk was higher in Chilean women.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Doenças das Artérias Carótidas
/
Espessura Intima-Media Carotídea
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo de prevalência
/
Fatores de risco
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Chile
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2016
Tipo de documento:
Artigo
País de afiliação:
Chile
Instituição/País de afiliação:
Hospital DIPRECA/CL
Similares
MEDLINE
...
LILACS
LIS