Adjunctive Hyperbaric Oxygen Therapy promotes successful healing in patients with refractory Crohn's disease

Feitosa, Marley Ribeiro; Féres Filho, Omar; Tamaki, Camila Mussolin; Perazzoli, Camila; Bernardes, Mário Vinícius Angelete Alvarez; Parra, Rogério Serafim; Rocha, José Joaquim Ribeiro da; Féres, Omar

Feitosa, Marley Ribeiro; Féres Filho, Omar; Tamaki, Camila Mussolin; Perazzoli, Camila; Bernardes, Mário Vinícius Angelete Alvarez; Parra, Rogério Serafim; Rocha, José Joaquim Ribeiro da; Féres, Omar.

Feitosa, Marley Ribeiro; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
Féres Filho, Omar; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
Tamaki, Camila Mussolin; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
Perazzoli, Camila; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
Bernardes, Mário Vinícius Angelete Alvarez; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
Parra, Rogério Serafim; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
Rocha, José Joaquim Ribeiro da; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
Féres, Omar; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR

Acta cir. bras ; 31(supl.1): 19-23, 2016. tab, graf

Artigo em Inglês | LILACS | ID: lil-779764

ABSTRACT

ABSTRACT

PURPOSE: To investigate de adjunctive effect of Hyperbaric Oxygen Therapy in a group of patients with refractory Crohn's disease. METHODS: A total of 29 subjects with refractory Crohn's disease were submitted to daily sessions of Hyperbaric Oxygen Therapy, in a 2800 Sechrist Monoplace Hyperbaric Chamber (Sechrist, USA) pressurized to 2.4 ATA. Each session lasted 2 hours. The endpoint was closure of enterocutaneous fistulas and complete healing of Pyoderma Gangrenosum and perineal Crohn's disease. RESULTS: A total of 829 HBOT sessions were performed and no complications were noted. Overall success rate was 76% (22 cases). Pyoderma Gangrenosum and enterocutaneous fistulas had the highest successful healing rates (100% and 91%, respectively). Perineal Crohn's disease healing rate was 65%. CONCLUSION: Adjunctive Hyperbaric Oxygen Therapy promoted satisfactory healing in a group of patients with refractory Crohn's disease.

Assuntos

Humanos; Masculino; Criança; Adulto; Pessoa de Meia-Idade; Idoso; Adulto Jovem; Cicatrização; Doença de Crohn/terapia; Fístula Intestinal/terapia; Pioderma Gangrenoso/terapia; Oxigenoterapia Hiperbárica/métodos; Fatores de Tempo; Estudos Prospectivos; Reprodutibilidade dos Testes; Resultado do Tratamento; Terapia Combinada; Oxigenoterapia Hiperbárica/estatística & dados numéricos

Crohn Disease; Cutaneous Fistula; Hyperbaric Oxygenation; Pyoderma Gangrenosum

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Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Cicatrização / Doença de Crohn / Fístula Intestinal / Pioderma Gangrenoso / Oxigenoterapia Hiperbárica Tipo de estudo: Estudo observacional / Fatores de risco Limite: Adulto / Idoso / Criança / Humanos / Masculino Idioma: Inglês Revista: Acta cir. bras Assunto da revista: Cirurgia Geral / Procedimentos Cir£rgicos Operat¢rios Ano de publicação: 2016 Tipo de documento: Artigo País de afiliação: Brasil Instituição/País de afiliação: University of São Paulo/BR

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