Serum lipid profile and clinical characteristics of patients with xanthelasma palpebrarum
An. bras. dermatol
;
91(4): 468-471, July-Aug. 2016. tab
Artigo
em Inglês
| LILACS
| ID: lil-792440
ABSTRACT
Abstract Background:
Although many factors are involved in the etiology of xanthelasma palpebrum, lipid disorder is strongly associated with its induction. Xanthelasma palpebrum, the most common type of xanthoma, usually presents in middle-aged females and results in aesthetic problems.Objective:
To evaluate thelipid profile and important clinical aspects of xanthelasma palpebrum patients.Methods:
In this descriptive study, we enrolled 42xanthelasma palpebrumpatients, and 42 cases of non-inflammatory skin disorders as thecontrol group, matched for age and gender.The clinical characteristics of the patients and fasting serum lipid profile were recorded for both groups. The data obtained were analyzed using SPSS-16.Results:
Xanthelasma palpebrum was found more commonly in middle-aged females with disease onset of less than 1 year, and without significant familial history of xanthoma. Furthermore,xanthelasma lesionswere most often seen in the upper lid with mild extension and was rarely associated with systemic disease. There was no statistically significant difference between two groups regarding hypertriglyceridemia (p= 0.231) and hypercholesterolemia (p= 0.302). The mean serum levels of cholesterol (221.51±60.4 mg/dl), triglyceride (185.98±71.1 mg/dl) and VLDL (37.7±17.6 mg/dl) were significantly higher and themedian HDL (36.2 (31, 41) mg/dl) level was lower in thepatient group.Conclusion:
In our study, hypercholesterolemia and hypertriglyceridemia did not reveal a significant difference between thepatient and control groups; however, mean serum values for cholesterol, triglyceride, VLDL and HDL showed a significant difference between the two groups. Therefore, in addition to lipid abnormality, other factors could be involved in the pathogenesis of xanthelasma palpebrum.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Triglicerídeos
/
Xantomatose
/
Colesterol
/
Doenças Palpebrais
Tipo de estudo:
Estudo de etiologia
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
An. bras. dermatol
Assunto da revista:
Dermatologia
Ano de publicação:
2016
Tipo de documento:
Artigo
País de afiliação:
Irã
Instituição/País de afiliação:
Kermanshah University of Medical Sciences/IR
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