Antimicrobial activity pf kaurenoic acid derivatives substituted on carbon-15
Braz. j. med. biol. res
;
22(9): 1127-9, 1989. tab, ilus
Artigo
em Inglês
| LILACS
| ID: lil-83188
ABSTRACT
The antibacterial and antifungic activities of two kaurenic acids, ent kaurenoic acid and cinnamoylgrandifloric acid isolated from a hexane extract of aerial parts of Mikania laevigata, were investigated and compared with the activities of other kaurenic acid-derivatives substituted on carbon-15. Only acetylgrandifloric acid (en-kaur-16-en-15 alfa-acetyloxy-19-oic) and its epimer xylopic acid (ent-kaur-16-4n-15 beta-acetyloxy-19-oic) displayed significant antibacterial activity at concentrations >=250 microng/ml., the 15 alfa epimer being the most active
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LILACS (Américas)
Assunto principal:
Bactérias
/
Diterpenos
/
Fungos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1989
Tipo de documento:
Artigo
/
Congresso e conferência
/
Documento de projeto
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