Pattern of acquisition of rotavirus antibody in children followed up from birth to the age of three years
Rev. Soc. Bras. Med. Trop
;
22(1): 25-9, jan.-mar. 1989. ilus
Artigo
em Inglês
| LILACS
| ID: lil-87195
ABSTRACT
Nine hundred and forty-eight serum samples from 83 children living in Belem, Brazil, collected within their first three years oflife, were tested for the presence of groupspecific rotavirus-antibody by an enzyme-linked immunosorbent assay (Elisa) blocking-test. Passively transferred maternal antibody lasted about two and half months; subsenquentely, low levels of rotavirus antibody started to appear at seven months, reaching a peak at eleven months of age. From one year onwards positivity gradually increased, reaching highest values at 34 months of life. Individual responses were examined in sera from 61 children who were followed up since birth to three years of age 38 (62,3%) of them developed a long-term immunity following first infection; eleven (18.0%) children developed a short-term immunity after first infection by rotavirus; seven (11.5%) had no antibody response within their first three years of life; and 5 (8.2%) showed positive antibody response from birth to three years old
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Índice:
LILACS (Américas)
Assunto principal:
Rotavirus
/
Anticorpos Antivirais
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
/
Recém-Nascido
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
1989
Tipo de documento:
Artigo
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