Absence of zinc cytotoxicity: Effect of short-term zinc oral administration on rat gastric mucosa
Braz. j. med. biol. res
;
23(6/7): 519-23, 1990. ilus
Artigo
em Inglês
| LILACS
| ID: lil-92196
RESUMO
Zinc ions have been reported to stabilize cellular membranes, protecting the gastric mucosa against a wide variety of ulcerative agents. The treatment with zinc sulfate intragastrically administered as one dose (20 mg/Kg body weight) daily for 30 consecutive days did not modify the normal aspect of rat gastric mucosa as observed by electron sanning microscopy. Furthermore, the X-ray microanalysis of the lysosome content performed on different gastric mucosa cells did not show the zinc element. These results suggest that zinc ion is a relatively nontoxic element for the rat gastric mucosa
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Índice:
LILACS (Américas)
Assunto principal:
Sulfatos
/
Zinco
/
Mucosa Gástrica
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1990
Tipo de documento:
Artigo
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