GAD-immunoreactive neurons are preserved in the hippocampus of rats with spontaneous recurrent seizures
Braz. j. med. biol. res
;
23(6/7): 555-8, 1990. ilus
Artigo
em Inglês
| LILACS
| ID: lil-92202
ABSTRACT
In the present glutamate decarboxylase immunoreactivity (GAD-IR) was used to quantify GABAergic neurons in the hippocampus of rats exhibiting spontaneous recurtent seizures following pilocarpine-induced status epilepticus. Histological examination demonstrated marked neuronal damage to hippocampal neurons. However, in the same region, GAD-IR neurons were preserved. the present data demonstrate a selective resistance of GABAergic neurons to status epilepticus-induced neuronal damage, suggesting that loss of hippocampal GABAergic neurons does not underlie the recurrence of seizures in these animals
Buscar no Google
Índice:
LILACS (Américas)
Assunto principal:
Pilocarpina
/
Convulsões
/
Estado Epiléptico
/
Epilepsias Parciais
/
Ácido gama-Aminobutírico
/
Glutamato Descarboxilase
/
Hipocampo
/
Neurônios
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1990
Tipo de documento:
Artigo
/
Congresso e conferência
Similares
MEDLINE
...
LILACS
LIS