Development of a species-specific ELISA for Brazilian PIY-Viper venoms
Braz. j. med. biol. res
; 23(6/7): 585-8, 1990. ilus
Article
em En
| LILACS
| ID: lil-92208
Biblioteca responsável:
BR26.1
RESUMO
Antigenic cross-reactivity between venoms of the genus Bothrops has been shown to be an extensive problem. However, some venom components are species-specific. In this study we have produced species-specific antivenoms against some members of the genus Bothrops. Monospecific rabbit antivenoms (IgG) were absorbed on venom affinity adsorbents. The species-specificity was tested by ELISA assays and immunoblots. The results of both assays showed complete species-specificity in some cases and highly increased species-specificity in others. These reagents can be used to determine the envenomating species in snake bite patients as an aid to improved serotherapy
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Índice:
LILACS
Assunto principal:
Imunoglobulina G
/
Ensaio de Imunoadsorção Enzimática
/
Antivenenos
/
Venenos de Crotalídeos
Limite:
Animals
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Braz. j. med. biol. res
Assunto da revista:
BIOLOGIA
/
MEDICINA
Ano de publicação:
1990
Tipo de documento:
Article
/
Congress and conference