Histochemical and histological analysis of the leydig cells of cats treated with a supraphysiological dose of LH-RH analog
Braz. j. med. biol. res
;
23(9): 819-22, 1990. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-92402
RESUMO
An LH-RH analog (des-Gly10, [D-Trp6]-LH-RH A) was administered to adult male cats for 67 days (20 microng/Kg,sc) in order to study its inhibitory effects on the structure of Leydig cells, as deter,mined by histological and histochemical-morphometric techniques. Histological examination showed that LH-RH A promotes a decrease in the volume of the interstitial tissue. In addition, Leydig cell nuclei exhibited marked structural alterations. Morphometric analyses utilizing histochemistry of the enzyme 3-ß-hydroxysteroid dehydrogenase (3-ß-HOST-D) as a marker of Leydig cells also demostrated a signifcant decrease of the relative volume occupied by the Leydig cells isn the testis
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Índice:
LILACS (Américas)
Assunto principal:
Testículo
/
Hormônio Liberador de Gonadotropina
/
3-Hidroxiesteroide Desidrogenases
/
Células Intersticiais do Testículo
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1990
Tipo de documento:
Artigo
/
Congresso e conferência
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