Tratamiento de la enfermedad de Hodgkin: protocolo nacional de drogas antineoplásicas: informe preliminar / Treatment of Hodgkin's disease: National Protocol on Antineoplastic Drugs: preliminary report
Rev. méd. Chile
;
119(1): 11-21, ene. 1991. tab
Artigo
em Espanhol
| LILACS
| ID: lil-98176
ABSTRACT
We report preliminary results of treatment of Hodgkin disease according to the National Protocol on Antineoplastic Drugs. 37 males and 22 females with a median age of 34 years (range 16 to 76) were treated. Patients with stages I or II received radiotherapy alone or chemotherapy (C-MOPP) followed by radiotherapy. Patients with stages III or IV received radiotherapy and chemotherapy or alternating courses of D-MOPP and ABVD. Complete remission was observed in 74% of 39 patients completing full therapy. Complete remission was more common in patients with nodular sclerosis without B symptoms and under 45 years of age. Actuarial survival at 22 months was 79%, significantly higher for patients with nodular sclerosis compared to patients with lymphocytic depletion. Different treatments in patients at stages I an II or III and IV gave comparable results. Complications included infection with the Chickenpox-Zoster virus, pneumonia and fever of Unknown origin. Mortality was associated to older age, complications of treatment or failure to comply with therapy
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Índice:
LILACS (Américas)
Assunto principal:
Doença de Hodgkin
/
Protocolos de Quimioterapia Combinada Antineoplásica
Tipo de estudo:
Guia de Prática Clínica
/
Estudo prognóstico
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
1991
Tipo de documento:
Artigo
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