Age-associated changes of memory (CD45RO+) and naive (CD45R+) T cells
Braz. j. med. biol. res
;
24(3): 275-9, mar. 1991. tab
Artigo
em Inglês
| LILACS
| ID: lil-99565
ABSTRACT
The total number of lymphocytes and the percentage of CD45RO+ (putative memory T cell) and CD45R+ (putative naive T cell) were determined in 15 cord blod samples, 66 healthy children ranging in a age from 1 to 18 years, 16 adults (23-59 years) and 16 aged individuals (60-96 years). The total number of lymphocytes decreased with age and reached the adult range in children to the adult group,white the percentage of CD45RO+ Tcells was low in cord blood and increased with age.No significant difference was observed between the adult and the aged groups for either lymphocyte subset. These data support the view that CD45RO+ and CD45R+ T-cell subsets represent maturational stages of T cells
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Índice:
LILACS (Américas)
Assunto principal:
Envelhecimento
/
Linfócitos T
/
Antígenos CD
/
Subpopulações de Linfócitos T
/
Antígenos de Histocompatibilidade
Tipo de estudo:
Fatores de risco
Limite:
Adolescente
/
Adulto
/
Aged80
/
Criança
/
Criança, pré-escolar
/
Humanos
/
Lactente
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1991
Tipo de documento:
Artigo
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