Healthy aged persons had a better adrenocortical function.

ABSTRACT

The present study was carried out in the department of physiology, Mymensingh Medical College, Mymensingh, Bangladesh during the period of July 2004 to June 2005 to estimate basal cortisol level in healthy aged persons and to explore association between aging and antiaging and adreno cortical status. A total number of 60 healthy subjects aged 60 and above 60 years old were included in this study. Twenty three (23) normal healthy subjects of aged 20-30 years were taken as control group. Estimation of serum cortisol level of both study and control group was done by radioimmunoassay (RIA) in centre for nuclear medicine and ultrasound, Mymensingh Medical College Hospital, Mymensingh, Bangladesh. Statistical analysis was done by SPSS program using unpaired students't' test between two groups. The results showed that there is no statistically significant difference in mean serum cortisol level of study group when compare to control group. The study depicts that subjects possessed better adrenocortical function and seems to be associated with good health and a high level of function despite advancing age.