Distribution of age-specific rotavirus antibody in human: a hospital-based study in Calcutta.

ABSTRACT

Sera obtained from 332 non-diarrhoeic individuals belonging to different age groups were tested by enzyme-linked immunosorbent assay method for detection of rotavirus antibody. All the sera were found to contain rotavirus antibody in varying titres, the highest being recorded in neonates which declined to the lowest by the age of 6 months with a rapid rise during the next 5 years. This study indicates the acquisition of rotavirus antibody in different age groups.