Optimal age for measles vaccination.
J Indian Med Assoc
;
2002 Jan; 100(1): 24-6
Artigo
em Inglês
| IMSEAR
| ID: sea-103468
ABSTRACT
Children in the age groups of 6-9 (group I) and >9-12 months (group II, control) 75 in each group, sex-matched were studied for antimeasles antibodies IgG and IgM by ELISA technique, before immunisation with Schwarz strain of measles vaccine. IgG antibodies were found in 66% in group I and none in group II, indicating the waning of maternal antibodies at an early age which come down before 6 months of age. After administration of measles vaccine to both the groups seroconversion was estimated at intervals of 4 weeks and 6 months after vaccination. Antimeasles IgM antibodies increased after vaccination and decreased 6 months after vaccination in both groups. Antimeasles IgG antibodies showed a significant increase in both groups. Increase was high in group II. This shows that anti-IgG antibodies to measles increased with age. The study shows the disappearance of protective level of immunisation at an early age. Seroconversion following vaccination at the age of 6 months is low, and hence a booster dose is recommended at 15 months.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Feminino
/
Humanos
/
Masculino
/
Imunoglobulina G
/
Imunoglobulina M
/
Ensaio de Imunoadsorção Enzimática
/
Vacina contra Sarampo
/
Fatores Etários
/
Imunização Secundária
/
Lactente
Idioma:
Inglês
Revista:
J Indian Med Assoc
Ano de publicação:
2002
Tipo de documento:
Artigo
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