Comparison between ELISA and ICT- MycoDot in adult pulmonary tuberculosis.
Artigo
em Inglês
| IMSEAR
| ID: sea-1038
ABSTRACT
The present study was conducted to see the diagnostic efficacy of serum anti-TB IgG antibody detection in adult pulmonary tuberculosis (TB) by ELISA and Immunochromatography test (ICT) method using commercially available diagnostic kit (Pathozyme TB complex and MycoDot test respectively). This case-control study included 48 cases of adult pulmonary TB within the age range of 15-65 years. Among them, 22 (45.9%) were AFB positive confirmed cases, 12 (25.0%) were AFB negative clinically diagnosed cases before treatment and 14 (29.1%) were clinically diagnosed cases on treatment. Age and sex matched 33 controls were also included, of which 19 (57.6%) were healthy and 14 (42.4%) were sick with non-specific pulmonary infection. Overall sensitivity and specificity of ELISA were 60.42% & 96.97% (p<0.001) and those of MycoDot as 72.92% & 93.94% (p<0.001). Rate of both ELISA and MycoDot positive were higher among clinically diagnosed cases on treatment with respective values as 71.42% and 85.71%. Respective values among AFB positive confirmed TB cases were 68.18% and 72.72%. As, both ELISA and MycoDot yielded be used as a confirmatory test for TB.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Kit de Reagentes para Diagnóstico
/
Tuberculose Pulmonar
/
Testes Imunológicos
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Imunoglobulina G
/
Ensaio de Imunoadsorção Enzimática
/
Estudos de Casos e Controles
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
Idioma:
Inglês
Ano de publicação:
2006
Tipo de documento:
Artigo
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