Effect of histamine on wound healing.
Indian J Physiol Pharmacol
;
1991 Jul; 35(3): 180-2
Artigo
em Inglês
| IMSEAR
| ID: sea-106257
ABSTRACT
Using incision, excision and dead space wound models in rats, a study was conducted on the effect of histamine on wound healing. Exogenous histamine given either ip or locally was without any effect. Semicarbazide as (histamine synthesis inhibitor) suppressed healing process (breaking strength of skin incision wound), decreased breaking strength and hydroxyproline content of granulation tissue and delay in period of epithelization. On the other hand compound 48/80 (a promoter of histamine forming capacity) was found to promote wound healing. Exogenous histamine (topical) reversed the anti-healing effect of semicarbazide on incision and excision wounds.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Ratos Endogâmicos
/
Semicarbazidas
/
Cicatrização
/
Feminino
/
Masculino
/
Carcinógenos
/
Histamina
/
P-Metoxi-N-metilfenetilamina
/
Tecido de Granulação
Idioma:
Inglês
Revista:
Indian J Physiol Pharmacol
Ano de publicação:
1991
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS